What is Rejuran, and why do so many people visiting Korea ask for it? This guide explains the Rejuran skin booster — often called the “salmon DNA injection” — what it does, how Rejuran HB plus differs from Rejuran Healer, how it feels, how long the bumps last, and what Rejuran costs in Seoul.
International patients usually ask us:
“What exactly is Rejuran?”
“Is it a filler?”
“How long will the bumps last if I have Rejuran on my trip?”
The short answer: Rejuran is a Korean skin booster made from PN (polynucleotide), purified from salmon DNA. It is injected into the skin to support the skin’s own repair, improving texture, fine lines, pores and hydration over time. It does not add volume like a filler. Small bumps appear at the injection points and usually last about 3 days to a week.
What is Rejuran?
Rejuran is an injectable skin booster developed in Korea by PharmaResearch. Its key ingredient is PN, or polynucleotide — fragments of DNA purified from salmon. Because PN is highly compatible with human tissue, it is used to support the skin’s natural regeneration.
That is why Rejuran is often called the “salmon injection” or “salmon DNA skin booster.” In Korea it has become one of the most requested treatments for skin quality, and it is now increasingly known among visitors from the US, Europe and Southeast Asia.
How does Rejuran work in the skin?
Rejuran works from the inside out, in four steps:
■ 1. Placed in the dermis
PN is injected point by point into the dermis, the layer under the skin surface.
■ 2. Supports skin cells
PN supports fibroblast activity — the cells that build collagen and elastin.
■ 3. Helps the skin repair
It helps calm irritated skin and supports the recovery of a damaged skin barrier.
■ 4. Texture, pores and hydration improve
Over the following weeks, fine lines, enlarged pores and thin, tired-looking skin gradually improve. Results vary with skin condition and the number of sessions.
Is Rejuran a filler?
No. A filler adds volume to change shape. Rejuran does not fill or reshape the face; it improves the quality of the skin itself. Your features stay the same — the skin simply looks smoother, more hydrated and healthier.
This is also why Rejuran pairs well with Thermage FLX: Thermage tightens the deeper layers, while Rejuran refines the skin closer to the surface.
What is the difference between Rejuran HB plus and Rejuran Healer?
There are several types of Rejuran. At our clinic we mainly use three:
| Type | Ingredients | Best for | Price (VAT incl.) |
|---|
| Rejuran HB plus | PN + hyaluronic acid + lidocaine | Whole face, including under the eyes | From KRW 290,000 (1cc) · KRW 1,750,000 (7cc full face) |
| Rejuran Healer | PN only | Mainly the neck | KRW 650,000 (4cc) |
| Lip Rejuran HB plus | PN + hyaluronic acid + lidocaine | Lip lines and dryness | KRW 400,000 (1cc) |
Prices as of October 2026, The H Faceup Clinic, Seoul.
For the face we recommend Rejuran HB plus. The added hyaluronic acid gives an immediate boost of hydration, and the lidocaine makes it much more comfortable than the original. Rejuran Healer contains PN only and is mainly used for the neck.
Book a Rejuran consultation on WhatsApp
Reply in English · Your plan is decided in person after Dr. Hwang examines you
What does Rejuran improve?
Rejuran is chosen for skin quality rather than lifting. Common reasons include:
• Fine lines and crepey texture
• Thin, delicate skin under the eyes
• Enlarged pores and uneven texture
• Dull, dehydrated skin
• Skin that feels sensitive or easily irritated
If your main concern is sagging along the jawline or cheeks, Rejuran alone is not the right tool. In that case Thermage FLX, or Thermage and Rejuran together, is usually a better plan.
Does Rejuran hurt, and how long do the bumps last?
Rejuran HB plus contains lidocaine, and numbing cream can be applied before treatment, so most patients find it very manageable. Dr. Hwang injects by hand, adjusting depth and spacing for each area, which also helps keep discomfort and marks to a minimum.
What to expect afterwards:
■ Small bumps
Small raised bumps appear at the injection points. They usually last about 3 days to a week.
■ Bruising
Small bruises can occasionally appear and may last 1 to 2 weeks.
■ Daily life
You can go sightseeing and fly as normal. If you have a wedding, an event or important photos, allow 1 to 2 weeks after Rejuran.
How should I prepare for Rejuran, and what should I avoid afterwards?
These are the same instructions we give patients at the clinic.
■ Before Rejuran
• Stop using “Reedle Shot” or similar microneedle skincare products 1 week before.
• Avoid aspirin for 2 weeks before treatment.
• Avoid heavy drinking the night before.
■ After Rejuran
• You can wear makeup the same day. Wash gently with lukewarm water so the treated area is not irritated.
• Avoid saunas, jjimjilbang and other hot places for 1 week.
• Avoid smoking, alcohol and hard exercise for 1 week as much as possible.
• Avoid scrubs and active skincare products for 3 to 4 weeks.
• If you notice a rash, itching or stinging, take the medication we prescribe and contact us.
If you are also having Thermage FLX, it is done first on the same day — Thermage should not be performed within a week after injections.
Why do people get Rejuran in Korea?
Rejuran was developed in Korea, and Korean clinics have more experience with it than anywhere else. Prices in Seoul are also usually lower than in many other countries.
But with Rejuran, technique matters as much as the product. At The H Faceup Clinic, Dr. Hwang In-sung, a Rejuran Key Doctor and Clinical Advisor, has personally administered more than 10,000cc of Rejuran, and our clinic is a Rejuran SVIP clinic. Every Rejuran treatment is injected by hand — not by machine — so the depth, spacing and amount can be adjusted for the eyes, cheeks and forehead individually. Genuine products are opened in front of you.
Many international patients also combine Rejuran with Thermage FLX in the same visit. Thermage FLX 600 shots + Rejuran HB plus 7cc is KRW 3,500,000 as a set. Read more in our guide to planning Thermage in Seoul.
What is Rejuran: frequently asked questions
What is Rejuran made of?
Rejuran’s key ingredient is PN (polynucleotide), purified from salmon DNA. Rejuran HB plus also contains hyaluronic acid and lidocaine.
Is Rejuran the same as a filler?
No. Rejuran does not add volume or change your face shape. It improves skin texture, fine lines, pores and hydration.
Which is better, Rejuran HB plus or Rejuran Healer?
For the face and under the eyes we recommend Rejuran HB plus, which is more comfortable and more hydrating. Rejuran Healer is mainly used for the neck.
How long do Rejuran bumps last?
Usually about 3 days to a week. Small bruises can occasionally last 1 to 2 weeks.
What should I avoid after Rejuran?
For 1 week, avoid saunas and jjimjilbang, smoking, alcohol and hard exercise. Avoid scrubs and active skincare for 3 to 4 weeks. Makeup is fine the same day.
How much does Rejuran cost in Seoul?
At our clinic, Rejuran HB plus starts at KRW 290,000 for 1cc, and 7cc for the full face is KRW 1,750,000, VAT included. See how this compares with prices abroad in our Rejuran price guide.
Can I have Rejuran and Thermage on the same day?
Yes. Thermage FLX firms the deeper layers first, and Rejuran then refines the surface. It is our most chosen combination.
Considering Rejuran in Seoul?
The H Faceup Clinic is a Thermage FLX and Rejuran clinic in Gangnam, Seoul. Dr. Hwang In-sung consults and treats every patient personally, and has administered more than 10,000cc of Rejuran by hand.
If you are not sure whether Rejuran, Thermage or both suit your skin, book a consultation — Dr. Hwang will examine your skin in person and decide the right plan with you.
The H Faceup Clinic
5F, 480 Gangnam-daero, Gangnam-gu, Seoul
1-minute walk from Sinnonhyeon Station Exit 3 (Line 9)
※ Information and prices as of October 2026. Results, discomfort and recovery vary between individuals, and the right treatment should be decided after a consultation with the doctor. If you have a known allergy to fish or salmon, or to lidocaine, please tell the doctor before treatment.
Medical review: Dr. Hwang In-sung, Rejuran Key Doctor · Clinical Advisor, The H Faceup Clinic (Rejuran SVIP clinic)
References: PharmaResearch, Rejuran product information
Chat with us on WhatsApp
Rejuran at The H Faceup Clinic
See all Thermage & Rejuran prices
The H Faceup Clinic on Google Maps
What is Rejuran, and why do so many people visiting Korea ask for it? This guide explains the Rejuran skin booster — often called the “salmon DNA injection” — what it does, how Rejuran HB plus differs from Rejuran Healer, how it feels, how long the bumps last, and what Rejuran costs in Seoul.
International patients usually ask us:
“What exactly is Rejuran?”
“Is it a filler?”
“How long will the bumps last if I have Rejuran on my trip?”
The short answer: Rejuran is a Korean skin booster made from PN (polynucleotide), purified from salmon DNA. It is injected into the skin to support the skin’s own repair, improving texture, fine lines, pores and hydration over time. It does not add volume like a filler. Small bumps appear at the injection points and usually last about 3 days to a week.
Rejuran is an injectable skin booster developed in Korea by PharmaResearch. Its key ingredient is PN, or polynucleotide — fragments of DNA purified from salmon. Because PN is highly compatible with human tissue, it is used to support the skin’s natural regeneration.
That is why Rejuran is often called the “salmon injection” or “salmon DNA skin booster.” In Korea it has become one of the most requested treatments for skin quality, and it is now increasingly known among visitors from the US, Europe and Southeast Asia.
Rejuran works from the inside out, in four steps:
■ 1. Placed in the dermis
PN is injected point by point into the dermis, the layer under the skin surface.
■ 2. Supports skin cells
PN supports fibroblast activity — the cells that build collagen and elastin.
■ 3. Helps the skin repair
It helps calm irritated skin and supports the recovery of a damaged skin barrier.
■ 4. Texture, pores and hydration improve
Over the following weeks, fine lines, enlarged pores and thin, tired-looking skin gradually improve. Results vary with skin condition and the number of sessions.
No. A filler adds volume to change shape. Rejuran does not fill or reshape the face; it improves the quality of the skin itself. Your features stay the same — the skin simply looks smoother, more hydrated and healthier.
This is also why Rejuran pairs well with Thermage FLX: Thermage tightens the deeper layers, while Rejuran refines the skin closer to the surface.
There are several types of Rejuran. At our clinic we mainly use three:
Prices as of October 2026, The H Faceup Clinic, Seoul.
For the face we recommend Rejuran HB plus. The added hyaluronic acid gives an immediate boost of hydration, and the lidocaine makes it much more comfortable than the original. Rejuran Healer contains PN only and is mainly used for the neck.
Book a Rejuran consultation on WhatsApp
Reply in English · Your plan is decided in person after Dr. Hwang examines you
Rejuran is chosen for skin quality rather than lifting. Common reasons include:
• Fine lines and crepey texture
• Thin, delicate skin under the eyes
• Enlarged pores and uneven texture
• Dull, dehydrated skin
• Skin that feels sensitive or easily irritated
If your main concern is sagging along the jawline or cheeks, Rejuran alone is not the right tool. In that case Thermage FLX, or Thermage and Rejuran together, is usually a better plan.
Rejuran HB plus contains lidocaine, and numbing cream can be applied before treatment, so most patients find it very manageable. Dr. Hwang injects by hand, adjusting depth and spacing for each area, which also helps keep discomfort and marks to a minimum.
What to expect afterwards:
■ Small bumps
Small raised bumps appear at the injection points. They usually last about 3 days to a week.
■ Bruising
Small bruises can occasionally appear and may last 1 to 2 weeks.
■ Daily life
You can go sightseeing and fly as normal. If you have a wedding, an event or important photos, allow 1 to 2 weeks after Rejuran.
These are the same instructions we give patients at the clinic.
■ Before Rejuran
• Stop using “Reedle Shot” or similar microneedle skincare products 1 week before.
• Avoid aspirin for 2 weeks before treatment.
• Avoid heavy drinking the night before.
■ After Rejuran
• You can wear makeup the same day. Wash gently with lukewarm water so the treated area is not irritated.
• Avoid saunas, jjimjilbang and other hot places for 1 week.
• Avoid smoking, alcohol and hard exercise for 1 week as much as possible.
• Avoid scrubs and active skincare products for 3 to 4 weeks.
• If you notice a rash, itching or stinging, take the medication we prescribe and contact us.
If you are also having Thermage FLX, it is done first on the same day — Thermage should not be performed within a week after injections.
Rejuran was developed in Korea, and Korean clinics have more experience with it than anywhere else. Prices in Seoul are also usually lower than in many other countries.
But with Rejuran, technique matters as much as the product. At The H Faceup Clinic, Dr. Hwang In-sung, a Rejuran Key Doctor and Clinical Advisor, has personally administered more than 10,000cc of Rejuran, and our clinic is a Rejuran SVIP clinic. Every Rejuran treatment is injected by hand — not by machine — so the depth, spacing and amount can be adjusted for the eyes, cheeks and forehead individually. Genuine products are opened in front of you.
Many international patients also combine Rejuran with Thermage FLX in the same visit. Thermage FLX 600 shots + Rejuran HB plus 7cc is KRW 3,500,000 as a set. Read more in our guide to planning Thermage in Seoul.
What is Rejuran made of?
Rejuran’s key ingredient is PN (polynucleotide), purified from salmon DNA. Rejuran HB plus also contains hyaluronic acid and lidocaine.
Is Rejuran the same as a filler?
No. Rejuran does not add volume or change your face shape. It improves skin texture, fine lines, pores and hydration.
Which is better, Rejuran HB plus or Rejuran Healer?
For the face and under the eyes we recommend Rejuran HB plus, which is more comfortable and more hydrating. Rejuran Healer is mainly used for the neck.
How long do Rejuran bumps last?
Usually about 3 days to a week. Small bruises can occasionally last 1 to 2 weeks.
What should I avoid after Rejuran?
For 1 week, avoid saunas and jjimjilbang, smoking, alcohol and hard exercise. Avoid scrubs and active skincare for 3 to 4 weeks. Makeup is fine the same day.
How much does Rejuran cost in Seoul?
At our clinic, Rejuran HB plus starts at KRW 290,000 for 1cc, and 7cc for the full face is KRW 1,750,000, VAT included. See how this compares with prices abroad in our Rejuran price guide.
Can I have Rejuran and Thermage on the same day?
Yes. Thermage FLX firms the deeper layers first, and Rejuran then refines the surface. It is our most chosen combination.
The H Faceup Clinic is a Thermage FLX and Rejuran clinic in Gangnam, Seoul. Dr. Hwang In-sung consults and treats every patient personally, and has administered more than 10,000cc of Rejuran by hand.
If you are not sure whether Rejuran, Thermage or both suit your skin, book a consultation — Dr. Hwang will examine your skin in person and decide the right plan with you.
The H Faceup Clinic
5F, 480 Gangnam-daero, Gangnam-gu, Seoul
1-minute walk from Sinnonhyeon Station Exit 3 (Line 9)
※ Information and prices as of October 2026. Results, discomfort and recovery vary between individuals, and the right treatment should be decided after a consultation with the doctor. If you have a known allergy to fish or salmon, or to lidocaine, please tell the doctor before treatment.
Medical review: Dr. Hwang In-sung, Rejuran Key Doctor · Clinical Advisor, The H Faceup Clinic (Rejuran SVIP clinic)
References: PharmaResearch, Rejuran product information
Chat with us on WhatsApp
Rejuran at The H Faceup Clinic
See all Thermage & Rejuran prices
The H Faceup Clinic on Google Maps